John F. Toney, MD

Director, Infectious Disease Clinical Research

John.Toney@va.gov

Affiliation(s)

University of South Florida

Professor of Medicine

Tampa VA Research & Education Foundation

Board Member

Research

Research Area(s): Investigational phase 2/3 vaccines; Oral fecal microbiota transplant for clostridioides difficile infection; Investigational antibiotics for resistant organisms.

Research Population: Efficacy in older (50-90) age groups; VA populations

Research Methods: Clinical trials; Epidemiological studies

Collaboration

Dr. Toney is interested in collaborating with researchers with similar interests, especially with resistant Gram-negative bacteria or with investigational vaccines

Connect with Dr. Toney

Recent Funding History

Dates Title Funding Source and Type Role

2024 – Present

A Randomized, Double-blind, Placebo-Controlled Phase 3 Study of VE303 for Prevention of Recurrent Clostridioides Difficile Infection: The Restorative303 Study

Vedanta

PI

2017 – Present

Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics (VA INTREPID Study)

VA CSP PI

2023 – 2024

Comparison of Two Versus Three antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease (MAC2v3)

PCORI

Co-I

2020 – 2023 A Randomized, Double-blind, Placebo-controlled Phase 3 Study to Assess the Efficacy and Safety of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Aged 18 Years and Older – ENSEMBLE Study Fred Hutchinson PI
2017 – 2019 Optimal Treatment for Recurrent Clostridium difficile Infection. VA Cooperative Studies Program CSP #596 (VA OpTION Study). VA CSP PI
2014 – 2018 Efficacy, Immunogenicity, and Safety Study of Clostridium difficile Toxoid Vaccine in Subjects at Risk for C. difficile Infection Sanofi Pasteur PI
2006 – 2010 VA Cooperative grant CSP #403(c) Shingles Prevention Study (SPS) Long Term Persistance Study VA CSP PI
2005 – 2006 VA Cooperative grant CSP #403(b) Shingles Prevention Study (SPS) Placebo Patient Vaccination Study VA CSP PI
1998 – 2004 VA Cooperative grant CSP #403 Shingles Prevention Study VA CSP PI